Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section

Paropakar Maternity and Women's Hospital

Status: Unknown

Conditions: Hypotension; Spinal; Perfusion Index

Treatments: Device: Perfusion Index

Study type: Observational

Funder types: Other

Identifiers

NCT03319433

ParopakarMWH

Details and patient eligibility

About

Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion. Various methods and agents have been tried in order to address this problem. However, this calamity is far from over.

Perfusion index is one such attempt to address the problem of hypotension by predicting which group of parturient may develop hypotension. This is a type of non-invasive method of assessing the relative vascular tone with the use of pulse oximeter which calculates the ration of pulsatile versus the non-pulsatile component of the blood flow. During normal physiological changes in pregnancy, there is relative loss of vascular tone which predisposes this group of patient to sudden development of hypotension after the sympathetic block due to spinal anesthesia.

Thus, the aim of the study is to use the non-invasive perfusion index data to predict the occurrence of hypotension in a parturient so that helps us to guide fluid and other drug therapy to address the problem of hypotension.

Enrollment: 130 estimated patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. ASA II physical status.
2. Planned for elective LSCS
3. Gestational age >36 weeks and <41 weeks

Exclusion criteria

1. Patient's refusal.
2. Emergency LSCS.
3. Patient's with contraindications to spinal anesthesia
4. Patient with BMI >40, preeclampsia, placenta praevia.
5. Patients with comorbidities like cerebrovascular or cardiovascular disease, and gestational diabetes.

Trial design

130 participants in 2 patient groups

Group I (Perfusion Index <3.5)

Description:

Those parturient with perfusion index \<3.5 when baseline monitors are attached while the patient is being prepared for surgery.

Treatment:

Device: Perfusion Index

Group II (Perfusion index >3.5)

Description:

Those parturient with perfusion index \>3.5 when baseline monitors are attached while the patient is being prepared for surgery.

Treatment:

Device: Perfusion Index