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Prediction of Intrahospital Cardiac Arrest Outcomes (PREDIHCA)

K

Kepler University Hospital

Status

Completed

Conditions

Cardiac Arrest

Treatments

Diagnostic Test: CPC

Study type

Observational

Funder types

Other

Identifiers

NCT05466188
PREDIHCA

Details and patient eligibility

About

Intrahospital cardiovascular arrest is one of the most common causes of death in hospitalized patients. In contrast to extramural cases of cardiovascular arrest, hospitalized patients often have severe medical conditions that can affect the outcome of resuscitation. Nevertheless, survival rates from resuscitation are better in hospitals than outside, because there is often a rapid start of resuscitation measures and predefined resuscitation standards. Regular CPR training and the availability of defibrillators in all bedside units can also positively influence outcome. Despite these many efforts, survival rates, especially of patients with good neurological outcome, remained stable at low levels even within hospitals in recent years and did not improve.

Most outcome parameters are nowadays well known. (e.g., initial rhythm, age, early defibrillation, etc.) Nevertheless, we still do not know today how relevant the corresponding factors actually are, especially in relation to each other. One approach to this might be machine learning methods such as "random forest", which might be able to create a predictive model. However, this has not been attempted to date.

The hypothesis of this work is to find out if it is possible to accurately predict the probability of surviving an in-hospital resuscitation using the machine learning method "random forest" and if particularly relevant outcome parameters can be identified.

Design: retrospective data analysis of all data sets recorded in the resuscitation register of Kepler University Hospital.

Measures and Procedure: Review of the registry for missing data as well as false alarms of the CPR team and, if necessary, exclusion of these data sets; evaluation of the data sets using the machine learning method random forest.

Enrollment

668 patients

Sex

All

Ages

18 to 120 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All adults patients suffering cardiac arrest and having been resuscitated by the medical emergency team of the Kepler University Hospital, Linz, Austria in the period of 2006-01-01 to 2018-10-31.

Exclusion criteria

  • None.

Trial design

668 participants in 2 patient groups

Outcome CPC Positive
Description:
Outcome CPC Positive
Treatment:
Diagnostic Test: CPC
Outcome CPC Negative
Description:
Outcome CPC Negative
Treatment:
Diagnostic Test: CPC

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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