Prediction of Jaundice in Term Infants

NICHD Neonatal Research Network

Status: Completed

Conditions: Infant, Newborn; Jaundice

Study type: Observational

Funder types: NETWORK

Identifiers

NCT01203410

U10HD021373 (U.S. NIH Grant/Contract)

U10HD021415 (U.S. NIH Grant/Contract)

NICHD-NRN-0004

U10HD027853 (U.S. NIH Grant/Contract)

U01HD019897 (U.S. NIH Grant/Contract)

U10HD021364 (U.S. NIH Grant/Contract)

U10HD027880 (U.S. NIH Grant/Contract)

U10HD027856 (U.S. NIH Grant/Contract)

U10HD027851 (U.S. NIH Grant/Contract)

U10HD027881 (U.S. NIH Grant/Contract)

U10HD021385 (U.S. NIH Grant/Contract)

U10HD027904 (U.S. NIH Grant/Contract)

U10HD027871 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.

Full description

Jaundice occurs in most human neonates during the several days after birth. The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.

Enrollment: 535 patients

Sex: All

Ages: Under 8 hours old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Infants born via cesarean delivery (to ensure subjects would still be hospitalized and available for ETCOc measurement and blood sampling on day 3 postpartum)
• Delivery within each center's scheduled recruitment period (to maximize nursing availability and minimize cost)
• Birth weight >2500 g
• Gestational age >37 weeks

Exclusion criteria

• Any illness that would require admission to the neonatal intensive-care unit (NICU) within 8 hours of birth

Trial design

535 participants in 1 patient group

Cohort 1

Description:

Term infants \>2500g birthweight.