Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer（NSCLC）

Qian Chu

Status: Enrolling

Conditions: Neoadjuvant Therapy; NSCLC

Study type: Observational

Funder types: Other

Identifiers

NCT07388771

TJ-IRB202512147

Details and patient eligibility

About

This observational study aims to construct and validate the performance of a multimodal predictive model in forecasting the outcomes of neoadjuvant therapy in patients with NSCLC.

The core research question is: Can a multi-model approach predict outcomes of neoadjuvant therapy for non-small cell lung cancer and provide clinical recommendations?

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. pathologically diagnosed non-small cell lung cancer
2. The treatment plan is：receiving neoadjuvant chemo-immunotherapy during the study period, followed by surgical resection

Exclusion criteria

1. recurrent or metastatic lung cancer;
2. patients with other primary tumors

Trial design

500 participants in 2 patient groups

NSCLC with neoadjuvant therapy but without surgery

NSCLC with neoadjuvant therapy and surgery