Prediction of Post-Cesarean Section Pain (PPCSP)

University of Washington

Status: Unknown

Conditions: Postoperative Pain

Treatments: Other: Psychophysical testing, questionnaires, and genetics

Study type: Observational

Funder types: Other

Identifiers

NCT00799162

35115-A

Details and patient eligibility

About

The purpose of this study is to determine if dynamic psychophysical testing along with genetic screening will allow to identify pre-operatively women who will suffer severe acute pain post-operatively and the subset who may experience chronic pain following cesarean section.

Enrollment: 800 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women age 18-50 scheduled for an elective cesarean section (1st or 2nd cesarean section)

Exclusion criteria

Women who:

• have taken opioids, acetaminophen, or NSAIDs 48 hrs prior to psychophysical testing
• have had more than two previous cesarean sections
• have a vertical abdominal incision from a prior cesarean section
• are non-English speaking
• have mental health issues
• have a failure of spinal anesthetic and require conversion to general anesthesia
• have a vertical uterine incision performed during ongoing cesarean section
• have a previous vertical uterine scar discovered during ongoing cesarean section

Trial design

800 participants in 1 patient group

Women with a scheduled cesarean section

Treatment:

Other: Psychophysical testing, questionnaires, and genetics