Prediction of Undesired Obstruction in External Ventricular Drains. (EVD-OBS)

Nantes University Hospital (NUH)

Status: Enrolling

Conditions: External Ventricular Drain; Intraventricular Hemorrhage; Intensive Care Unit

Treatments: Other: Patients of intensive care unit; Other: Patients of surgical intensive care unit

Study type: Observational

Funder types: Other

Identifiers

NCT06466811

RC24_0074

Details and patient eligibility

About

Acute obstructive hydrocephalus often complicates intraventricular hemorrhage (IVH). The insertion of an external ventricular drain (EVD) is typically necessary in order to alleviate intracranial pressure by draining excess fluid. However, dysfunction of the EVD whether due to malposition or obstruction, can exacerbate hydrocephalus in an already compromised brain. EVD dysfunction must therefore be promptly detected and treated.

Consequently, identifying high-risk patients and closely monitoring them is imperative. While IVH is known to increase the risk of obstruction in the natural cerebrospinal fluid outflow tract, its association with ventricular drain obstruction remains unproven.

Enrollment: 640 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria :

Patient older than 18 years old,

• admitted to the ICU,
• with first EVD inserted for less than 12 hours,
• and brain imaging (CT or MRI) available in the timespan "24 hours before to 24 hours after" the EVD insertion.

Exclusion Criteria :

• EVD intentionally occluded immediately after its insertion,
• purulent cerebrospinal fluid
• Pregnant or breast-feeding patient
• Moribund patient or patient with decision of withholding or withdrawing life-sustaining treatment within the 12 hours
• Patient with no health insurance
• Patient under guardianship