Predictive Ability of Therapeutic Risk Factors in Pediatric and Adult Asthma Patients

GlaxoSmithKline (GSK)

Status: Completed

Conditions: Asthma

Treatments: Drug: Asthma treatment with an asthma-related medication and at least one asthma controller medication

Study type: Observational

Funder types: Industry

Identifiers

NCT01346852

112607

Details and patient eligibility

About

The purpose of this study is to assess the predictive ability of three asthma risk markers: the ratio of controller medication to total asthma medication, an albuterol only marker, and an oral corticosteroid use marker, as well as to compare the precision of these tools between adult and pediatric patient populations. This retrospective longitudinal analysis will use 2 different databases: a large managed care database and a large fee for service Medicaid database.

Enrollment: 101,437 patients

Sex: All

Ages: 4+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with asthma as determined by ICD-9 codes and asthma drug use
• at least 4 years of age
• use of at least 1 controller or at least 5 albuterol prescriptions in 12 months

Exclusion criteria

• Subjects with COPD or treatment for COPD

Trial design

101,437 participants in 2 patient groups

Pediatric participants

Description:

Pediatric participants (age 4 to 17) with a diagnosis of asthma

Treatment:

Drug: Asthma treatment with an asthma-related medication and at least one asthma controller medication

Adult participants

Description:

Adult participants (age 18 and older) with a diagnosis of asthma

Treatment:

Drug: Asthma treatment with an asthma-related medication and at least one asthma controller medication