Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer (DIP-CAOS)

Caen University Hospital

Status

Not yet enrolling

Conditions

Addiction Nicotine

Psychoactive Substance Use

Anxiety Disorder/Anxiety State

Symptoms and Signs

Neuropathic Pain

Pain, Chronic

Sleep

Alcohol Use Disorder

Treatments

Other: Questionnaire

Study type

Interventional

Funder types

Other

Identifiers

NCT05505188

2020-A01894-35

Details and patient eligibility

About

Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological components. Chronic pain affects 36% of patients at 6 months and 30% after this period. These pains are responsible for the consumption of level II and III analgesics in 53% of these patients. At the same time, after the end of treatment, nearly a quarter of patients continued to smoke and half still consumed alcohol at least twice a week.

The hypothesis of this research is to investigate the correlation between pain and the continuation of addictions, the occurrence of depressive states, asthenia and the alteration of the patients' global quality of life.

The investigators propose a two-center prospective cohort study to evaluate this hypothesis at 6 months after radiotherapy treatment.

This study is planned to include 120 patients with a first head and neck cancer whit radiotherapy as part of their treatment sequence. The expected duration of inclusion is 18 months.

The identification of factors affecting survival, quality of life and patient compliance is essential to determine appropriate management, particularly by creating appropriate therapeutic education programs.

Enrollment

120 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with a first Head and neck cancer whose therapeutic sequence involves radiotherapy
Patient over 18 years of age
Having given written consent
patient not previously treated with radiotherapy
Life expectancy > 3 months
World Health Organization (WHO) score < 3
Histologically proven Head and Neck cancer
Stable patient, with no signs of recurrence or other progressive neoplasia at the time of the examination
Patient treated with radiotherapy
Patient fluent in French

Exclusion criteria

Non-consenting patient
History of malignancy, other than treated and cured basal cell or cervical cancer
Patient who has had a salvage surgery other than lymph node removal
Patient with evidence of recurrence or other progressive neoplasia at the time of examination
Patient who has had previous mutilating surgery (causing sequelae of swallowing and eating)
Uncontrolled infectious pathology
Patient under 18 years of age
Patient who is not fluent in French
Patient with a psychiatric pathology that could disrupt the study or prevent the interpretation of the results.