Predictive Factors and Autonomy Level Change (MEMORA)

Civil Hospices of Lyon

Status: Enrolling

Conditions: Memory Impairment

Treatments: Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6

Study type: Interventional

Funder types: Other

Identifiers

NCT02302482

2014.868

Details and patient eligibility

About

The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.

Enrollment: 10,860 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who undergo a medical visit in the Memory Clinic for the 1st time
• Patients living at home or in housing
• Patients with memory impairment, at all stage of the disease

Exclusion criteria

• Patients in institution
• Patients under legal protection
• Patients with a hearing or visual impairment, which dot not allow to carry out the examination

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10,860 participants in 1 patient group

Functional autonomy level collection

Experimental group

Description:

Collection of the Functional autonomy level every 6 - 12 months by phone

Treatment:

Other: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6