Predictive Factors COVID-19 Patients (MI-COVID)

University of Milano Bicocca

Status: Withdrawn

Conditions: covid19

Treatments: Other: Predictive factors for clinical response in patients with COVID-19.

Study type: Observational

Funder types: Other

Identifiers

NCT04427345

MI-COVID

Details and patient eligibility

About

This is a monocentric retro-prospective observational study that will be conducted on all COVID19 positive patients hospitalized at the S. Gerardo Hospital in Monza.

Full description

BACKGROUND:

The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic is severely testing the health systems of the most advanced countries. Clinicians are faced with a new pathology of an emerging virus. There is therefore an urgent need to collect real-time clinical data that informs about outcome predictive variables. Furthermore, there are currently no antiviral drugs approved for the treatment of SARS-CoV-2 infection, off-label therapies are being used with drugs already in use for other pathologies that have shown some efficacy in vitro, and some treatments obtained for compassionate use with other drugs that are being tested.

It is more than ever necessary to collect clinical practice data both retrospectively on the work done so far, and in a longitudinal perspective, and analyze them quickly to optimize current treatments and define protocols for the future. Having a good clinical data base also offers the possibility of collaborating with numerous international networks on translational research, which aims to correlate clinical data with virological and immunological data, aimed at the rapid identification of possible specific viral virulence factors, or particular immune structures of the guests who once again define the final clinical outcome.

STUDY DESIGN:

All COVID19 positive patients admitted to San Gerardo Hospital will be enrolled in the study.

After patient signs the informed consent, the following data will be collected:

• birth data
• sex
• demographic data
• comorbidity
• blood chemistry data at the entrance

A series of variables will then be collected relating to the treatment procedure, the therapies, the team's choice to maximize the care ceiling in the individual patient and the entire clinical study of the patient.

STATISTICAL ANALISYS:

Central tendency and dispersion measurements will be used for descriptive analysis of continuous variables while absolute and relative frequencies will be used to describe categorical variables.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 18 years old or above
• Diagnosis of SARS-CoV-2 pneumonia

Exclusion criteria

• Explicit refusal to participate in the study

Trial design

0 participants in 1 patient group

Covid19 infection related patients

Description:

Patients admitted to COVID wards of the S. Gerardo Hospital of Monza, including Intensive Care wards.

Treatment:

Other: Predictive factors for clinical response in patients with COVID-19.