Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients

Centre Hospitalier de Gonesse

Status: Not yet enrolling

Conditions: Alzheimer Disease; Cognitive Dysfunction; Mini-Mental State Examination; Neuropsychological Tests; Caregivers

Study type: Observational

Funder types: Other

Identifiers

NCT07122856

0114_NEUROLOGIE_TARGET MMSE

Details and patient eligibility

About

This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12 months. Researchers will review medical records from patients seen at the Memory Clinic of Gonesse Hospital and analyze information such as age, education, medical history, nutrition, mood, and caregiver burden. The goal is to better understand what influences early cognitive performance and how quickly it changes, to help improve patient care and planning.

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed diagnosis of Alzheimer's disease according to NIAA 2018 or IWG 2021 criteria
• At least two MMSE evaluations spaced 12 months apart
• Follow-up at the Memory Clinic of CH Gonesse

Exclusion criteria

• Presence of other neurodegenerative diseases (e.g., Frontotemporal Dementia, Multiple System Atrophy, Vascular Dementia, LATE)
• Patient has moved out of the study area (outside the CH Gonesse territory)