Predictive Factors of Autonomy Loss in Real-life Cohort (MEM-AURA)

Civil Hospices of Lyon

Status: Enrolling

Conditions: Memory Disorders

Treatments: Other: no intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT03894254

69HCL18_0613

Details and patient eligibility

About

The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The Investigators aim at developing a regional database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative staff and with the University hospital computer science departments.

The main objective is to study the predictive factors associated with change in functional autonomy level, measured every 6 to 12 months in centres across Region Auvergne Rhone-Alpes in France.

The real-life study population will consist in about 5400 patients with ADRD. The inclusion period will be of 3 years, the length of follow-up of each patient will be of 10 years max for a total study length of 13 years.

Enrollment: 5,400 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18 years and older, undergoing a medical visit in a memory center or neuro-cognition service
• Patients living at home or in housing
• Patients with memory impairment, at all stage of the disease

Exclusion criteria

• Patients in institution
• Patients under legal protection
• Patients with a hearing or visual impairment, which prevents carrying out examinations

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

5,400 participants in 1 patient group

Patients with subjective cognitive complaint or neurocognitive

Experimental group

Description:

: Real-life cohort patients with subjective cognitive complaint or neurocognitive disorders undergoing medical examination in memory centers, and for whom extensive evaluations will be performed for the study

Treatment:

Other: no intervention