Predictive Factors of Graft Detachment Following Dmek (PDF DMEKDETACH)

Centre Hospitalier Régional Metz-Thionville

Status: Completed

Conditions: Descemet Membrane Endothelial Keratoplasty; Graft Detachment; Pseudophakic Bullous Keratopathy; Fuchs' Endothelial Corneal Dystrophy

Treatments: Procedure: Descemet Membrane Endothelial Keratoplasty

Study type: Observational

Funder types: Other

Identifiers

NCT05531760

2022-10Obs-CHRMT

Details and patient eligibility

About

The aim of this study was to identify the predictive factors of graft detachment after Descemet Membrane Endothelial Keratoplasty (DMEK) surgery. This retrospective study was conducted on patients aged 18 years, with Fuchs' dystrophy (FECD) or pseudophakic bullous keratopathy (PBK), who were scheduled for DMEK or triple-DMEK (combined phacoemulsification and DMEK surgery). Patients with a history of surgery other than cataract surgery were excluded. The study was conducted between 2014 and 2022 and follow-up was for 3 months. The characteristics of patients with and without graft detachment following surgery were compared using logistic regression.

Enrollment: 170 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over 18 years of age with DMEK surgery

Exclusion criteria

• all associated eye surgery other than cataract surgery
• all existing anterior segment anomalies

Trial design

170 participants in 2 patient groups

DMEK-operated eyes without graft detachment

Description:

Eyes operated with DMEK without graft detachment

Treatment:

Procedure: Descemet Membrane Endothelial Keratoplasty

DMEK-operated with graft detachment

Description:

Eyes operated with DMEK with graft detachment

Treatment:

Procedure: Descemet Membrane Endothelial Keratoplasty