Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma

Hospital Israelita Albert Einstein

Status: Completed

Conditions: Uterine Leiomyoma; Exposure to Magnetic Field

Treatments: Procedure: Magnetic Resonance Image

Study type: Observational

Funder types: Other

Identifiers

NCT01468402

HIAE

Details and patient eligibility

About

The purpose of this study is to determine predictive factors in the pelvic magnetic resonance in the response of arterial embolization of uterine leiomyoma.

Full description

This study followed symptomatic premenopausal women with uterine leiomyoma who underwent uterine artery embolization (UAE). Treatment was accompanied by magnetic resonance imaging of both the volume of the entire uterus and the leiomyomas one month before and six months after UAE. This patients were treated at the Uterine Leiomyoma Sector of the Department of Obstetrics and Gynecology, Medicine College of the University of São Paulo. In this study, the investigators examined 179 leiomyomas in 50 patients.

Enrollment: 50 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ultrasound diagnosis of uterine leiomyoma
• presence of symptoms (menorrhalgia and/or pelvic pain)
• indication for UAE(the desire to keep the uterus and/or contraindications for surgery).

Exclusion criteria

• malignant genital neoplasms
• pelvic inflammatory disease
• allergy to iodinated contrast
• coagulopathy, renal failure
• vasculitis
• pelvic irradiation
• pregnancy
• subserosal leiomyoma with a pedicle smaller than 50% of diameter of the fibroid.

Trial design

50 participants in 1 patient group

Magnetic Resonanse Image

Description:

The leiomyomas were evaluated individually. MR was used to evaluate morphology: the radiological dimension(s) of the leiomyoma and uterus and the volume. The number of leiomyoma fibroid, and their location in the myometrium was classified. Perfusion and the characterization of the T2 signal were also evaluated.

Treatment:

Procedure: Magnetic Resonance Image