Predictive Models of Treatment Responses and Survival Outcomes in Patients With Soft Tissue Sarcoma

Sichuan University

Status: Enrolling

Conditions: Soft Tissue Sarcoma

Treatments: Other: Prediction model

Study type: Observational

Funder types: Other

Identifiers

NCT05171413

HX-20211156

Details and patient eligibility

About

The aim of this study was to developed and validated models to predict therapeutic responses and patients' survivals in patients with soft tissue sarcoma and compared these models with currently available models.

Full description

We performed a retrospective-prospective cohort study with the aim of developing and validating comprehensive models to predict treatment responses and survival outcomes in patients with biopsy-proven soft tissue sarcoma. Secondly, we aimed to compare the predictive accuracy with currently available noninvasive model.

Enrollment: 800 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Receiving no treatment before diagnosis
• With written informed consent

Exclusion criteria

• Clinical data missing
• Without written informed consent

Trial design

800 participants in 2 patient groups

Retrospective cohort

Description:

The internal cohort was retrospectively enrolled in West China Hospital, Sichuan University from June 2010 and December 2020. It is a training and internal validation cohort.

Treatment:

Other: Prediction model

Prospective cohort

Description:

The same inclusion/exclusion criteria were applied for the same center prospectively. It is an external validation cohort.

Treatment:

Other: Prediction model