Predictive Value of Bio-impedance Vector Analysis on Long-term Outcome in ICU Patients

Medical Centre Leeuwarden

Status: Completed

Conditions: Survival; Long-term Outcome

Study type: Observational

Funder types: Other

Identifiers

NCT04449796

nWMO 2018-312

Details and patient eligibility

About

Phase angle, derived from bioimpedance analysis (BIA), reflects tissue quality and quantity in which cell mass, membrane integrity and hydration state are represented. Phase angle, as a measure of body composition, changes with the physical condition of patients and is associated with survival in several disease states and during ICU admission. Aim of the study is to explore the predictive value of the phase angle for long term ICU outcome.

Full description

Phase angle, derived from bioimpedance analysis (BIA), reflects tissue quality and quantity in which cell mass, membrane integrity and hydration state are represented. Phase angle, as a measure of body composition, changes with the physical condition of patients and is associated with survival in several disease states and during ICU admission. Aim of the study is to explore the predictive value of the phase angle for long term ICU survival.

A single-centre prospective observational cohort will be performed with consecutive patients, elective and non elective, admitted to the ICU between 1st June 2018 and 1st June 2019. Demographic data, APACHE III, comorbidity and phase angle are collected and the ICU- , hospital- and 6 months survival will be registered.

Enrollment: 1,025 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients admitted to the ICU, elective and acute.

Exclusion criteria

• age below 18
• Length of stay at ICU < 6 hours
• All invalid bio-impedence analysis (BIA) measurements