Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer

Xi'an Jiaotong University

Status: Withdrawn

Conditions: Pulmonary Embolism; Lung Cancer

Treatments: Diagnostic Test: CTPA (computed tomography pulmonary angiography)

Study type: Observational

Funder types: Other

Identifiers

NCT06017271

XJTU1AF2023LSK-269

Details and patient eligibility

About

The occurrence and progression of lung cancer is related to visceral adipose tissue (VAT). Epicardial adipose tissue (EAT) is a kind of VAT, producing a variety of inflammatory cytokines and adipokines, participating in the formation of local inflammation, promoting the formation of pre-thrombotic state, and leading to the occurrence of thromboembolism. Patients with lung cancer have increased inflammatory response and are more prone to suffer thrombosis. However, in lung cancer patients, the clinical correlation between EAT and pulmonary embolism has not been reported. Objective: To analyze the risk factors of poor prognosis in lung cancer patients with PE, and to explore the predictive value of EAT in pulmonary embolism events and death in lung cancer patients. Methods: EAT volume and density, as well as anthropometric and blood biomarkers, were evaluated in a sample of lung cancer patients, half with pulmonary embolism and half without. The incidence of adverse prognosis and related factors were followed up by telephone.

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The pathological diagnosis was lung cancer
• Pulmonary artery was evaluated by CTA during hospitalization.

Exclusion criteria

• Patients with incomplete clinical data
• Patients with no follow-up data
• Patients with a history of PE before diagnosis of lung cancer

Trial design

0 participants in 2 patient groups

PE group

Description:

The CTPA diagnosis suggest pulmonary embolism

Treatment:

Diagnostic Test: CTPA (computed tomography pulmonary angiography)

control group

Description:

The CTPA diagnosis did not suggest pulmonary embolism

Treatment:

Diagnostic Test: CTPA (computed tomography pulmonary angiography)