Predictive Value of Inflammatory Indexes and CHA2DS2-VASc Score for LVT in ANT-MI With Left Ventricular Dysfunction

Zhengzhou University

Status: Completed

Conditions: Acute Anterior Myocardial Infarction; Left Ventricular Thrombus; Left Ventricular Dysfunction

Treatments: Other: inflammatory indexes and CHA2DS2-VASc score

Study type: Observational

Funder types: Other

Identifiers

NCT04871126

CHA2DS2-VASc score

Details and patient eligibility

About

To investigate the predictive value of inflammatory indexes and CHA2DS2-VASc score for anterior myocardial infarction (ANT-MI) with left ventricular thrombus(LVT) (LVT).

Full description

The clinical data were collected from 371consecutive patients with ANT-MI in our hospital from January 2014 to January 2021.As a result,totally 62 patients with LVT were selected as the experimental group and 186 patients with non-LVT as the control group .The observation indexes included baseline data, coronary angiography, disease course, laboratory examination and auxiliary examination.Patients with severe organic disease and having previous history of left ventricular aneurysm( LVA) and LVT were excluded.Data was analyzed by software SPSS 22.0 for statistical analysis,and the logistic regression model was established.A P<0.05 was considered statistically significant, and the risk factors of LVT formation were retrospectively analyzed.

Enrollment: 371 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

acute anterior myocardial infarction with left ventricular dysfunction

Exclusion criteria

end-stage organic disease, thrombotic hematological disorders, previous anticoagulant use, and poor echogenicity

Trial design

371 participants in 2 patient groups

LVT group

Description:

left ventricular thrombus in acute anterior myocardial infarction patients with left ventricular dysfunction

Treatment:

Other: inflammatory indexes and CHA2DS2-VASc score

non-LVTgroup

Description:

acute anterior myocardial infarction patients with left ventricular dysfunction while without LVT

Treatment:

Other: inflammatory indexes and CHA2DS2-VASc score