Predictive Value of Periodic Repolarization Dynamics in Post-Infarction Patients (PRD-MI)

Thebiosignals.com

Status: Completed

Conditions: Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT02128477

BIO012014

Details and patient eligibility

About

Increased periodic repolarization dynamics (PRD) indicate increased risk of death in cardiac patients. This study thoughts to prospectively validate the prognostic value of PRD in post-infarction patients.

Full description

Periodic repolarization dynamics (PRD) reflect periodic changes of repolarization instability located in the low-frequency spectral range. Level of PRD can be assessed using a high resolution surface ECG recorded in the 12-leads of Frank leads configuration during resting conditions.

Increased levels of PRD have been associated with sympathetic overactivity and increased risk of mortality in survivors of acute myocardial infarction and patients undergoing a clinically indicated exercise test.

Enrollment: 754 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• previous myocardial infarction >4 weeks
• age >18 years

Exclusion criteria

• life expectancy < 1 year due to non-cardiac causes
• unable to give informed consent