Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage

Istanbul University

Status: Completed

Conditions: Anastomotic Leakage in Colon Surgery

Treatments: Procedure: Colon surgery

Study type: Observational

Funder types: Other

Identifiers

NCT02361918

CTF-EH0001

Details and patient eligibility

About

Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.

Full description

To search for a biomarker, which might be able to predict rectal anastomotic leakage before its clinical presentation. Serum procalcitonin, C-reactive protein, and drain fluid culture, IL-6 and TNF-α levels were evaluated in 50 consecutive patients with rectal cancer who underwent low anterior resection with colorectal anastomosis.

Enrollment: 50 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient underwent to colonic resection and had drain

Exclusion criteria

• other patients

Trial design

50 participants in 2 patient groups

Anastomotic leakage

Description:

Patient had anastomotic leakage

Treatment:

Procedure: Colon surgery

No anastomotic leakage

Description:

Patient had no anastomotic leakage

Treatment:

Procedure: Colon surgery