Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery (ODFAPO)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Postoperative Atrial Fibrillation; Strains

Study type: Observational

Funder types: Other

Identifiers

NCT06054360

PI2023_843_0048

Details and patient eligibility

About

The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute myocardial infarction, and death. While the role of the left atrium (LAF) in the pathophysiology of POAF is now well-established, the part of the right atrium (RA) remains poorly understood. Recent studies suggest a correlation between RA function and POAF.

RA function can be assessed by transthoracic echocardiography (TTE) with dedicated software for measuring the RA strain (RAS). RA function is thus divided into three phases: reservoir (RASr), conduit, and contraction. Numerous studies have demonstrated that a significant alteration in RAS predicts POAF in various clinical contexts. Therefore, it is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery.

It is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery.

Enrollment: 334 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patient (>18 years old)
• The patient was hospitalized at the Amiens University Hospital for scheduled aortocoronary bypass grafting under cardiopulmonary bypass.
• Echocardiographic image quality enabling the measurement of RAS parameters
• Patient affiliation to a social security scheme
• Patient/proxy information and collection of their non-opposition.

Exclusion criteria

• Patients participating in an interventional study may modify the incidence of POAF.
• History of atrial fibrillation or flutter.
• Valvular and ascending aorta cardiac surgery
• Urgent cardiac surgery.
• Presence of tricuspid insufficiency greater than grade 2.
• Left ventricular ejection fraction lower than 50%.
• Patient receiving circulatory mechanical assistance before surgery.
• Dependency on ventricular and atrial pacing by an internal or external cardiac pacemaker during the echocardiographic examination.