Predictors and Outcomes of In-hospital HFpEF in AMI Patients

Xiangjun Yang

Status: Unknown

Conditions: Predictor; Heart Failure With Preserved Ejection Fraction; Acute Myocardial Infarction; Prognosis

Treatments: Combination Product: clinical characteristics, previous history, laboratory bio-markers, echocardiographic measurements, angiographic findings,clinical outcomes

Study type: Observational

Funder types: Other

Identifiers

NCT03351179

FirstSoochowU

Details and patient eligibility

About

This retrospective observation is to investigate the incidence,clinical outcomes and prognosis of hospitalized heart failure with preserved ejection fraction (HFpEF) in patients with acute myocardial infarction(AMI).

Full description

1. Patients with first AMI undergoing primary percutaneous coronary intervention (PCI) in our hospital since January 2013 were retrospectively evaluated. The enrolled subjects were divided into two groups (AMI patients with HFpEF and AMI patients without HF).
2. The investigator collected the clinical data of participants' demographics (age, sex), previous history,risk factors for AMI (hypertension, hyperlipidemia, diabetes mellitus, smoking and stroke), laboratory biomarkers, echocardiographic measurements, clinical characteristics,medical procedures and treatments, as well as in-hospital complications.
3. Two sub-investigators independently analyzed these data by using SPSS software.

Enrollment: 500 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• First AMI patients undergoing PCI with HFpEF or without HF.

Exclusion criteria

• First AMI patients with heart failure with reduced ejection fraction.
• First AMI patients with severe inflammatory diseases, valvular heart disease, non-cardiac caused symptoms, serious hepatic and renal failure, congenital cardiomyopathy,or pericardial diseases.

Trial design

500 participants in 2 patient groups

AMI patients with HFpEF

Treatment:

Combination Product: clinical characteristics, previous history, laboratory bio-markers, echocardiographic measurements, angiographic findings,clinical outcomes

AMI patients without HF

Treatment:

Combination Product: clinical characteristics, previous history, laboratory bio-markers, echocardiographic measurements, angiographic findings,clinical outcomes