Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula

Assiut University

Status: Not yet enrolling

Conditions: Acute Respiratory Failure Patients on NIV and HFNC

Study type: Observational

Funder types: Other

Identifiers

NCT05864898

NIV and HFNC

Details and patient eligibility

About

Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.

Full description

Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients.

There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate.

Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients.

Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to :

1. RR > 25 cycle / min
2. using accessory muscles and paradoxical breath.
3. PaO2 / FiO2 ratio < 300

Exclusion criteria

1. Absolute indication for intubation like coma, haemodynamically unstable... etc
2. Contr-indication of NIV like untreated Pneumothorax.