Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

Sohag University

Status: Not yet enrolling

Conditions: Intracranial Atherosclerosis; Posterior Circulation Brain Infarction; Stroke, Ischemic

Treatments: Other: we are aiming to develop a Scoring system based on certain variables derived from both groups

Study type: Observational

Funder types: Other

Identifiers

NCT06453252

Soh-Med-24-05-04MD

Details and patient eligibility

About

Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT). The aim of the study is to develop and validate a scoring system for pre-thrombectomy diagnosis of ICAD in posterior circulation large vessel/distal medium vessel occlusion strokes (LVOs/DMVOs).

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adult ≥18 years
2. Patient with posterior circulation strokes who underwent mechanical thrombectomy.

Exclusion criteria

1. Patients with anterior circulation stroke.
2. Patients with intracranial hemorrhage
3. Patients without baseline radiological data.
4. Extracranial large vessel atherosclerosis related strokes.

Trial design

150 participants in 2 patient groups

ICAD group

Description:

includes ICAD-related stroke made when a smooth-bordered lesions leading to delayed perfusion on conventional-angiography (without competing stroke etiology) or when irregular-surfaced lesions involving the target vessel during mechanical thrombectomy were unveiled (with or without competing stroke etiology).

Treatment:

Other: we are aiming to develop a Scoring system based on certain variables derived from both groups

Non-ICAD cases (controls)

Description:

Non-ICAD cases (controls) includes patients with posterior circulation stroke attributed to stroke etiologies other than ICAD.

Treatment:

Other: we are aiming to develop a Scoring system based on certain variables derived from both groups