Predictors of Intracranial Hemorrhage in ARDS Patients on ECMO

Charité University Medicine Berlin

Status: Unknown

Conditions: Extracorporeal Membrane Oxygenation Complication; ARDS, Human

Treatments: Other: complication versus no complication

Study type: Observational

Funder types: Other

Identifiers

NCT04142775

ChariteMM

Details and patient eligibility

About

Intracranial hemorrhage is is a rare, but critical incident in patients with acute lung failure undergoing ECMO therapy. Predictors of intracranial hemorrhage are yet to be defined to identify patients at (high) risk. This retrospective analysis investigates the predictive value and validity of parameters and specific risk factors of critically ill ARDS patients treated with ECMO.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ARDS following Berlin definition (mild, moderate, severe)
• ECMO therapy (veno-venous cannulation)

Exclusion criteria

• ECMO, other than VV
• ICH at initiation of ECMO
• no cerebral CT scan at any time

Trial design

1,000 participants in 2 patient groups

intracranial hemorrhage (ICH)

Description:

ARDS patients treated with ECMO developing ICH

Treatment:

Other: complication versus no complication

no intracranial hemorrhage

Description:

ARDS patients treated with ECMO not developing ICH