Predictors of Node Positivity in Endometrial Cancer

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Status: Enrolling

Conditions: Endometrial Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05793333

142020

Details and patient eligibility

About

To investigate the role of histological and moleculr profile of endometrial cancer patietns in predicting the risk of nodal metastases in endometrila cancer patients.

Enrollment: 200 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent
• Histologically confirmed endometrila cancer
• Data on molecular genomic profiling (POLE mutated, p53 abnormalities, MMRd/MSI-H, and NSMP)
• Data on histological characteristics of the ttumor
• Execution of sentinel node mapping
• Data on sentinel node status (negative vs. positive)

Exclusion criteria

• Stage IVB endoemtrial cancer
• consent withdraw