Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia

Universidade do Porto

Status: Enrolling

Conditions: Carotid Endarterectomy

Treatments: Procedure: carotid endarterectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04347785

248-18

Details and patient eligibility

About

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.

The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.

Full description

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.

The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.

All consecutive patients from a tertiary referral center who underwent CEA for carotid artery stenosis (CS) and consecutive patients who presented alterations in the neurologic examination after ICA clamping during CEA are selected. The control patients, submitted to the same procedure but with no neurologic alterations, are consecutively selected.

Enrollment: 206 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• carotid endarterectomy under regional anesthesia
• Postclamping carotid deficit

Exclusion criteria

• carotid stenting

Trial design

206 participants in 2 patient groups

Neurologic deficit

Description:

All consecutive patients from a tertiary referral center who underwent CEA for carotid artery stenosis who presented alterations in the neurologic examination after ICA clamping during CEA area selected

Treatment:

Procedure: carotid endarterectomy

control

Description:

The control patients are submitted to the same procedure but with no neurologic alterations, are consecutively selected. a 1 to 1 ratio is used

Treatment:

Procedure: carotid endarterectomy