Predictors of Postoperative Atrial Fibrillation After CABG (CODA-AF)

Kun Hua

Status: Active, not recruiting

Conditions: Coronary Artery Disease; Atrial Fibrillation New Onset

Treatments: Procedure: CABG

Study type: Observational

Funder types: Other

Identifiers

NCT05888168

2023065X

Details and patient eligibility

About

This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Full description

Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.

Enrollment: 15,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 years or older.
• Patients who underwent CABG.

Exclusion criteria

• Patients with a history of preoperative atrial fibrillation or other significant arrhythmias.
• Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG.
• Patients who cannot provide informed consent or lack adequate follow-up information.

Trial design

15,000 participants in 2 patient groups

POAF

Description:

This group will consist of patients who have developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

Treatment:

Procedure: CABG

Non-POAF

Description:

This group will consist of patients who have not developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

Treatment:

Procedure: CABG