Predictors of the Metabolic Effect of Sleep Loss (SDBO)

The University of Chicago

Status: Completed

Conditions: Obstructive Sleep Apnea (OSA); Apnea; Obesity

Treatments: Other: Extension; Other: Restriction

Study type: Interventional

Funder types: Other

Identifiers

NCT00965783

#15207A

1 RO1 IIL075025

Details and patient eligibility

About

To test whether baseline levels of slow wave activity (SWA) during sleep are lower in obese adults, and even lower in persons with sleep disordered breathing (SDB) compared to lean adults.

To compare levels of SWA in individuals in relation to their sleep time, blood pressure, heart rate, and markers of glucose metabolism.

Enrollment: 30 patients

Sex: All

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy,
• normal sleepers,
• lean, overweight,
• obese,
• pre menopausal

Exclusion criteria

• no shift workers or night-shift workers,
• no mental health disorders,
• no acute or chronic health conditions (stable, well controlled hypertension are accepted),
• no hormonal treatments,
• no substances that may interfere with sleep,
• problems with sleep

Trial design

30 participants in 2 patient groups

1

Experimental group

Description:

Sleep time restriction

Treatment:

Other: Restriction

2

Experimental group

Description:

Sleep time extension

Treatment:

Other: Extension