Predictors of Treatment Outcome for Smokers With and Without Schizophrenia

Rutgers The State University of New Jersey

Status: Completed

Conditions: Tobacco Dependence

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00501007

K23DA018203 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The primary purpose of this investigation is to determine the predictive value of task persistence as measured by a mirror tracing task. A secondary purpose is to evaluate differences in task persistence in smokers with or without schizophrenia. It is hypothesized that task persistence in smokers in both diagnostic categories (schizophrenia and no schizophrenia) will predict tobacco dependence treatment outcome at one and six months. It is also hypothesized that smokers with schizophrenia will show lower levels of task persistence after controlling for other motor skills than smokers without schizophrenia.

Full description

Please see brief summary above.

Enrollment: 203 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Current smokers must be over the age of 18,
• Must fit into the diagnostic groups schizophrenia / schizoaffective disorder; or the non-schizophrenia group.
• Must smoke at least 10 cigarettes per day
• Must be capable of giving informed consent as measured by Folstein Mini Mental Status Exam of at least 22.

Exclusion criteria

• Those unable to give informed consent.
• Psychotic disorders other than schizophrenia

Trial design

203 participants in 2 patient groups

Non-psychiatric smokers

Description:

Smokers not meeting criteria for Schizophrenia or Schizoaffective Disorder

Smokers with Schizophrenia

Description:

Smokers meeting criteria for schizophrenia or schizoaffective disorder