Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control

Baskent University

Status and phase: Completed; Phase 4

Conditions: Cesarean Section; Dehiscence

Treatments: Drug: paracetamol; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02369133

KA 13-180

Details and patient eligibility

About

The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive paracetamol on postoperative pain scores, patient satisfaction, total morfin consumption and the incidence of morfin-related side effects in patients undergoing cesarean section.

Enrollment: 60 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients between the ages of 20-40 years,
• ASA physical status 1-2 who underwent elective cesarean surgery during general anesthesia were included in the study

Exclusion criteria

• A history of allergy to any of the study medications (opiod, general anesthetic agents or paracetamol),
• history of opioid or paracetamol use,
• hepatic or renal failure,
• any psychological disorders,
• complications during cesarean section and unable to use PCIA device were excluded from the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Group Paracetamol (Group P),

Active Comparator group

Description:

Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group P (n = 30) received 1 g iv paracetamol

Treatment:

Drug: paracetamol

Group Saline (Group S)

Placebo Comparator group

Description:

Drugs were given intravenously by a nurse unaware of the study 15 min before surgery. Patients in group S (n = 30) received 100 ml iv %0,9 saline

Treatment:

Drug: Placebo