Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients

Asan Medical Center

Status: Completed

Conditions: Pain, Postoperative; Acute Pain; Preemptive Peripheral Nerve Block

Treatments: Drug: Intercostal nerve block; Drug: Ultrasound guided Rectus sheath block

Study type: Interventional

Funder types: Other

Identifiers

NCT03413280

2017-0301

Details and patient eligibility

About

The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).

After induction of general anesthesia, group of patient is decided randomly. In Group pre, RSB and ICNB are performed with 0.25% Ropivacaine 40ml before the operation. In Group post, RSB and ICNB are performed with 0.25% Ropivacaine 40ml after the operation.

Measure the NRS and compare the rescue analgesic dose used at 0, 0.5, 1, 2, 6, 9, 18, and 24 hours after arrival at the recovery room.

Enrollment: 200 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. adults between the ages of 20 and 80
2. scheduled laparoscopic cholecystectomy patient
3. ASA class 1 or 2
4. Patients who have voluntarily agreed in writing to participate in the trial

Exclusion criteria

1. Patient with side effects on local anesthetics or steroids
2. Patient who are taboo of peripheral nerve block such as blood clotting disorder, infection, etc.
3. Patients with uncontrolled medical or psychiatric problem
4. Patient does not agree to participate in the study
5. Patients who are pregnant or lactating
6. Patients whose visceral pain is expected to be too severe
7. Patients receiving a single laparoscopic cholecystectomy (including using a robot)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 2 patient groups

preoperative Rectus sheath block: group Pre

Experimental group

Description:

ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml Before surgical incision

Treatment:

Drug: Ultrasound guided Rectus sheath block

Drug: Intercostal nerve block

postoperative Rectus sheath block: group Post

Active Comparator group

Description:

ultrasound guided Rectus sheath block block with 0.25% ropivacaine 40ml After surgical incision

Treatment:

Drug: Ultrasound guided Rectus sheath block

Drug: Intercostal nerve block