Preemptive Local Anesthesia in Vaginal Surgery

Mayo Clinic

Status and phase: Completed; Phase 4

Conditions: Pain, Postoperative

Treatments: Drug: bupivacaine and epinephrine; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT00318292

63-06

Details and patient eligibility

About

Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a vaginal hysterectomy with suspension sutures.

Enrollment: 90 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Women undergoing vaginal hysterectomy with McCall's culdoplasty

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 2 patient groups, including a placebo group

PLA

Experimental group

Description:

Active preemptive local analgesia.

Treatment:

Drug: bupivacaine and epinephrine

Placebo

Placebo Comparator group

Description:

Placebo for preemptive local analgesia.

Treatment:

Drug: Placebo