Preference of Genetic Polymorphism and Pharmacokinetics

The Chinese University of Hong Kong

Status: Completed

Conditions: HIV

Study type: Observational

Funder types: Other

Identifiers

NCT01658371

CRE-2008.180

Details and patient eligibility

About

Genetic polymorphism affects plasma concentration of antiretroviral therapy in HIV patients. The investigators investigate the prevalence of genetic polymorphism affecting efavirenz metabolism and the corresponding pharmacokinetics of different genotypes.

Full description

Eligible patients are invited to donate blood samples for pharmacokinetic study and genotype analysis

Enrollment: 100 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Southern Chinese HIV patients on efavirenz

Exclusion criteria

• Refuse to sign consent, HIV patients not on efavirenz

Trial design

100 participants in 1 patient group

efavirenz

Description:

HIV patients on efavirenz