Pregabalin for Alcohol Dependence

St. Petersburg Bekhterev Research Psychoneurological Institute

Status and phase: Completed; Phase 4

Conditions: Alcoholism

Treatments: Drug: Pregabalin; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02205879

BRPI-PGBL-A01

Details and patient eligibility

About

The study hypothesis is: Pregabalin is superior to placebo in preventing relapse to drinking and reducing drinking severity

Full description

This is a two cell double blind placebo controlled randomized clinical trial of pregabalin for alcohol dependence

Enrollment: 100 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alcohol Dependence by ICD-X criteria

Exclusion criteria

• Severe co-morbid psychiatric and somatic diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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100 participants in 2 patient groups, including a placebo group

pregabalin

Experimental group

Treatment:

Drug: Pregabalin

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo