Pregnancy Outcome and Vitamin D Level Among Vitamin D Supplementation During Pregnancy

Rajavithi Hospital

Status and phase: Completed; Phase 3

Conditions: Pregnancy Outcome Among Vitamin D Supplementation During Pregnancy

Treatments: Drug: Vitamin D 2; Drug: Placebo drug

Study type: Interventional

Funder types: Other

Identifiers

NCT04591847

121/2563

Details and patient eligibility

About

To compared pregnancy outcome (Serum vitamin D level in mother and infant , preeclampsia rate, preterm birth rate, Infant birth weight, Infant length , APGAR score) between pregnant women who were given vitamin D supplementation and pregnant women who were given placebo

Enrollment: 60 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Thai female
• Singleton pregnancy
• Age at 18 years old or more
• Gestational age at 18-22 weeks
• Accept to enroll

Exclusion criteria

• Pregnant women who not planned to delivery at Rajavithi hospital
• Abnormal kidney function
• Use antiepileptic drugs , or vitamin D supplementation
• Allergy to vitamin D
• Who were diagnosed as vitamin D deficiency

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups

Vitamin D supplemented group

Experimental group

Description:

Vitamin D2 20000 IU 1 tab oral weekly start at GA 18 -22 weeks until delivery

Treatment:

Drug: Vitamin D 2

Placebo group

Experimental group

Description:

Placebo drug (Appearance same as Vitamin D2) 1 tab oral weekly start at GA 18 -22 weeks until delivery

Treatment:

Drug: Placebo drug