Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer

Istituto Clinico Humanitas

Status: Completed

Conditions: IVF; Embryo Transfer; Fertility Issues

Study type: Observational

Funder types: Other

Identifiers

NCT05364528

12022

Details and patient eligibility

About

The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques.

The secondary end points include the evaluation of the difficult transfer rates.

Full description

The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols.

Any blastocysts that underwent preimplantation genetic testing will be excluded from the analysis, as well as embryos derived from gamete donation or those imported from other centers.

Data are gathered using a specific internal web-based database, which allows to organize, store and readily retrieve information about patients and IVF cycle.

Enrollment: 8,127 patients

Sex: Female

Ages: 18 to 43 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• IVF procedure
• Fresh and frozen single blastocyst transfer

Exclusion criteria

• Any blastocysts that underwent PGS testing
• Embryos derived from gamete donation
• Embryos imported from other centers

Trial design

8,127 participants in 2 patient groups

clinical pregnancies with direct catheter

Description:

Clinical pregnancies occurred after fresh and frozen blastocyst transfers using direct technique.

clinical pregnancies with afterload catheter

Description:

Clinical pregnancies occurred after fresh and frozen blastocyst transfers using afterload technique.