Pregnancy Rates in IVF After Ovulation Triggering With Recombinant or Urinary Human Chorionic Gonadotrophin (HCG)

Universitair Ziekenhuis Brussel

Status and phase: Unknown; Phase 3

Conditions: VEGF; Embryonic Development; Pregnancy

Treatments: Drug: 250 mcg recombinant HCG; Drug: 10000 IU urinary HCG

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00954265

rec-HCG 002

Details and patient eligibility

About

To access whether the ovulation triggering with rec-HCG instead urinary-HCG has any impact on the blastulation rate and pregnancy rate of patients undergoing IVF treatment

Enrollment: 130 estimated patients

Sex: Female

Ages: 20 to 36 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• FSH<12,
• normal sperm,less than 36y,
• single blastocyst transfer

Exclusion criteria

• endometriosis stage 3&4,
• pco

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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130 participants in 2 patient groups

Urinary-HCG group

Active Comparator group

Description:

These patients received u-HCG for ovulation triggering during ovarian stimulation for IVF

Treatment:

Drug: 10000 IU urinary HCG

Recombinant HCG group

Experimental group

Description:

These patients received rec-HCG for ovulation triggering during ovarian stimulation for IVF

Treatment:

Drug: 250 mcg recombinant HCG