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Prehabilitation and Coronary Artery Bypass Grafting

R

Riphah International University

Status

Completed

Conditions

Coronary Artery Bypass Graft

Treatments

Other: Active Comparator: Control group
Other: Resistant training (Prehabilitation)

Study type

Interventional

Funder types

Other

Identifiers

NCT04993976
Rec/00980 Wajeeha Sahar

Details and patient eligibility

About

To evaluate the effects of Prehabilitation Resistance training on frailty and functional capacity in mild to moderate clinically frail patients awaiting Coronary Artery Bypass Grafting) CABG. This study will contribute to describing the effect of resistance training in mild to moderate frails patients and were directed to be the part of cardiac rehabilitation and define the effects of cardiac prehabilitation and to check whether the effects of resistance training or routine training is similar for quality of recovery in mild to moderate frails patients which undergone CABG.

Full description

In literature, Coronary Artery Bypass Graft (CABG) is a form of heart surgery that redirects blood around clogged arteries to increase blood flow and oxygen to the heart. During CABG surgery, the surgeon uses a portion of a healthy vessel (either an artery or vein) from the leg, chest, or arm to create a bypass around the clogged artery. During CABG surgery with cardiopulmonary bypass, a heart-lung machine artificially maintains circulation blood and oxygenation while the surgeon operates on the heart. It includes exercise, lifestyle changes, education, and emotional support. It can help improve patient's health and enable them to live a more active life after the patient has had a heart attack or heart surgery or if the patient has long-term heart problems such as heart failure.

The time spent waiting for cardiac surgery to be scheduled is a period of great uncertainty for a patient. There appears to be heightened anxiety regarding the inclusion of physical activity in this time period, mainly as a result of their current cardiac condition or diagnosis

Enrollment

74 patients

Sex

All

Ages

40 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients undergoing elective primary isolated coronary artery bypass grafting,

    • Patients with double and triple-vessel coronary artery disease.
    • Mild to moderately frail patients with a clinical frailty score of 5 -6 at the time of accepting surgery at the outpatient cardiothoracic surgical clinic.

Exclusion criteria

  • Patient with musculoskeletal disability and neurological disability affecting respiratory rate.

    • Patient with renal dysfunction requiring dialysis, use of immunosuppressive treatments during the 30-day period before surgery,
    • Left ventricular ejection fraction <30%
    • concomitant valve disease
    • Patient having dysrhythmias or pacemaker dependent
    • Those patients who are severely frail (CFS 7-9)

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

74 participants in 2 patient groups

Prehabilitation group
Experimental group
Description:
Strength training along with warm-up and cool down for 8 weeks
Treatment:
Other: Resistant training (Prehabilitation)
Control group
Active Comparator group
Description:
Supervised Standard care plan for 8 weeks
Treatment:
Other: Active Comparator: Control group

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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