Prehabilitation Prior to Surgery for Kidney Tumors (Pre-KiT)

Herlev and Gentofte Hospital

Status: Enrolling

Conditions: Elderly (people Aged 65 or More); Renal Cancer; Stage I Renal Cell Cancer; Renal Cell Cancer; Prehabilitation; Kidney Cancers

Treatments: Other: Prehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT06745609

H-24066449

Details and patient eligibility

About

The goal of this clinical trial is to examine if one month of general health optimization before surgery for kidney tumors can help participants recover more quickly from surgery.

The optimization process is called prehabiliation, and will last one month. It consists of

1. A comprehensive health assessment
2. Assisted smoking cessation
3. A home exercise program.

The investigators will compare an intervention group receiving one month of prehabilitation with a control group receiving the standard of care.

Some of the main questions the investigators want to answer are

• Are participants in the intervention group more satisfied with their quality of recovery after surgery?
• Do participants in the intervention group maintain more of their physical abilites compared to the control group?

Enrollment: 60 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 65 years or older
• cT1 kidney tumor, scheduled for either partial or radical nephrectomy.
• Clinical Frailty Scale 3-6

Exclusion criteria

• It is determined by an attending physician, or at a multi-disciplinary team-conference, that a 2-4 week postponement of surgery will not be beneficial for the participant.
• Participant does not understand Danish og English

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Control group

No Intervention group

Description:

Participants in the control group are scheduled for surgery in compliance with the Danish cancer patient pathway guarantees (within 14 days).

Intervention with Pre-KiT prehabilitation

Experimental group

Description:

Participants in the intervention group are scheduled for surgery after four weeks of Pre-KiT prehabilitation. The prehabilitation consists of a geriatric guided assessment with relevant targeted interventions, a home exercise program and assisted smoking cessation.

Treatment:

Other: Prehabilitation