Prematurity and Ophthalmological Changes

Ankara City Hospital

Status: Completed

Conditions: Myopia; Retinopathy of Prematurity

Treatments: Device: axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)

Study type: Observational

Funder types: Other

Identifiers

NCT06452524

AKU749K

Details and patient eligibility

About

Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity

Full description

Aims: To compare functional (visual acuity and refractive error) and anatomical (biometric values, foveal and choroidal thickness) ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity (ROP).

Settings and Design: Prospective Cross-Sectional Study

Methods and Material: The study was conducted prospectively in the ophthalmology department of Ankara Bilkent City Hospital. Subjects were divided into three groups: 29 children who were treated with laser photocoagulation (ROP-TxGroup), 26 children who developed ROP and did not need treatment (ROP-non-TxGroup), and 25 children who did not develop ROP (Premature Group). The 27 healthy children with a history of full-term born (Control Group), who were in a similar age group for 'control eye examination', were accepted as the control group. A total of 107 patients and 211 eyes were included in the study. Non-cycloplegic and cycloplegic refraction, best corrected visual acuity (BCVA), keratometry, axial length (AL) and anterior chamber depth (ACD), optical coherence tomography (OCT) macular and OCT subfoveal choroidal measurements were performed in all cases.

Enrollment: 211 patients

Sex: All

Ages: 5 to 13 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Children with a history of ROP

Exclusion criteria

Stage 4-5 ROP, Presence of media opacities (such as cataract) Ocular trauma or ocular surgery Hydrocephalus or grade 3 and above intracerebral hemorrhage, Uncooperative children

Trial design

211 participants in 4 patient groups

ROP-Tx Group

Description:

less than 37 weeks were divided into three groups: 29 children born prematurely who were treated with laser photocoagulation

Treatment:

Device: axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)

ROP-non-Tx Group

Description:

26 children who developed ROP and did not need treatment

Treatment:

Device: axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)

Premature Group

Description:

25 children who did not develop ROP

Treatment:

Device: axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)

Control Group

Description:

27 healthy children with a history of full-term born

Treatment:

Device: axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)