Prenatal and Postnatal Ultrasonographic Evaluation of Myelomeningocele to Predict Post-Surgical Outcomes

Superior University

Status: Active, not recruiting

Conditions: Myelomeningocele

Treatments: Diagnostic Test: G.E HEALTHCARE ultrasound machine with high-resolution convex probe

Study type: Observational

Funder types: Other

Identifiers

NCT07048691

MSAHSW/Batch-Fall23/909

Details and patient eligibility

About

Myelomeningocele (MMC), also known as open spina bifida, is a serious congenital condition in which the cord and meninges protrude through the spinal column's defective bony encasement due to a defective closure of the posterior portion of the neural tube between the fourth week of pregnancy.

Full description

The formation of the defect is influenced by both genetic and environmental factors, while the exact cause is yet unknown. There is currently no effective treatment for this common and debilitating central nervous system (CNS) dysfunction.

Enrollment: 20 patients

Sex: All

Ages: 28 to 40 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gestational age 3rd trimester, Lesion between T1 and S1, Hindbrain herniation and Normal karyotype

Exclusion criteria

• Multiple gestation pregnancy
• Other fetal anomalies unrelated to myelomeningocele
• History of incompetent cervix, Other serious maternal medical conditions
• Inability to adhere to travel and follow-up requirements
• Contraindication to surgery and Inability to meet trial psychosocial criteria.

Trial design

20 participants in 1 patient group

G.E HEALTHCARE ultrasound machine with high-resolution convex probe

Treatment:

Diagnostic Test: G.E HEALTHCARE ultrasound machine with high-resolution convex probe