Prenatal Diagnosis of the Fetal Esophageal or Intestinal Atresia (DANATRESIA)

Poitiers University Hospital

Status: Completed

Conditions: Antenatal Management of the Fetal Gastrointestinal Atresia

Treatments: Procedure: scheduled delivery at a tertiary center

Study type: Observational

Funder types: Other

Identifiers

NCT05362604

DANATRESIA

Details and patient eligibility

About

Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes.

Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive pregnancies, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.

Full description

Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes.

Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive participants, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.

Enrollment: 51 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all pregnancies affected by fetal esophageal, duodenal or intestinal atresia referred to our prenatal diagnosis unit
• all newborns managed for such atresia in our unit of pediatric surgery

Exclusion criteria

• termination of pregnancy,
• stillbirth,
• the false positive cases

Trial design

51 participants in 2 patient groups

prenatal

Description:

patients affected by confirmed fetal esophageal, duodenal or intestinal atresia and followed in our high-risk pregnancy unit, and scheduled for delivery between 38 and 39 weeks in our tertiary center, regardless of the patient's place of residence

Treatment:

Procedure: scheduled delivery at a tertiary center

postnatal

Description:

patients with unsuspected fetal atresia who delivered in their local hospitals: their newborns were transferred to our tertiary hospital within 24 hours and the mother had the option to be also transferred in order to follow her baby.