Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus. (MALROT)

University Hospital Center (CHU)

Status: Completed

Conditions: Mesenteric Pregnancy; Postnatal Complication

Treatments: Other: Fetal MRI; Other: Pediatric Follow up; Other: Postnatal abdominal ultrasound; Other: Ultrasound exam

Study type: Observational

Funder types: Other

Identifiers

NCT05148429

RECHMPL21_0684

Details and patient eligibility

About

Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus. This requires emergency surgery with a risk of digestive resection. Visualizing during pregnancy the normal or abnormal anatomical positionning of the mesenteric vessels could make it possible to diagnose this malrotation and prevent the occurrence of this complication.

The aim of the study is to study the neonatal outcome of fetus confirm to have an abnormal positionning of mesenteric vessels

Enrollment: 30 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women attending for 2nd trimester ultrasound
• Abnormal positionning of mesenteric vessels
• No other foetal malformation
• Singleton pregnancy
• Age >18 years

Exclusion criteria

• Chromosomal abnormality
• polymalformative syndrom
• Foetal malformation changing intestine disposition (gastroschisis, diaphragmatic hernia, heterotaxis...)

Trial design

30 participants in 1 patient group

Fetuses with abnormal positionning of mesenteric vessels

Description:

All pregnant women with abnormal positionning of mesenteric vessels during second trimester scan

Treatment:

Other: Fetal MRI

Other: Pediatric Follow up

Other: Postnatal abdominal ultrasound

Other: Ultrasound exam