Prenatal Ultrasound Screening of Intestinal Malrotation With a Higher Risk of Volvulus (VOLMES)

University Hospital Center (CHU)

Status: Completed

Conditions: Intestinal Malrotation

Treatments: Other: +/- prophylactic surgery; Other: Pediatric surgeon meeting; Other: MRI between 30-35 GA; Other: Postnatal abdominal ultrasound, barium enema and upper gastrointestinal

Study type: Observational

Funder types: Other

Identifiers

NCT03356314

RECHMPL17_0258

Details and patient eligibility

About

The aim of this study was to assess the value of an unusual relative position of the superior mesenteric artery (SMA) and vein (SMV) to screen intestinal malrotation with a higher risk of volvulus.

First, feasibility study was done to prove the reproducibility of ultrasound in diagnosis of anormal mesenteric vessels position.

A systematic screening of the mesenteric vessels position was performed at each pregnancy required ultrasound.

When the fœtus had an unusual position of the mesenteric vessels, an MRI was suggested between 30 and 35 GA and the couple met the pediatric surgery team.

Few days after birth, an abdominal ultrasound was achieved as well as a barium enema and upper gastrointestinal. If there were a hight probability of malrotation with a higher risk of volvulus, a prophylactic surgery was proposed. The children were flollowed up during 1 year.

Enrollment: 9,000 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pregnant women
• second or third trimester ultrasound.

Exclusion criteria

• fœtal ultrasound anomaly