Preoperative Arterial Embolization Before Oncologic Esophagectomy as a Technique for Ischemic Gastric Conditioning

Centre Hospitalier Universitaire de Saint Etienne

Status: Not yet enrolling

Conditions: Esophageal Cancer

Treatments: Other: Collecting data from the medical record

Study type: Observational

Funder types: Other

Identifiers

NCT06312839

IRBN032024/CHUSTE

Details and patient eligibility

About

This retrospective monocentric comparative study aims to assess the efficacy of preoperative ischemic conditioning, in preventing anastomotic leakage in esophageal cancer surgery. Two groups were included : a surgery-alone group (control group) and a PreopAE group (study group) treated with an embolization procedure before esophagectomy. Collected data included patient characteristics, embolization procedure details, surgical outcomes, and postoperative complications.

The primary outcome was the efficacy of preoperative ischemic conditioning in preventing anastomotic leakage, assessed through CT scans. Secondary outcomes included analyzing safety of ischemic gastric conditioning, hypertrophy of the gastroepiploic artery in embolized patients and comparing hospital stay length and postoperative mortality.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients older than 18 years with an indication for surgical esophagectomy with cervical anastomosis using the Lewis Santy technique or three stages approach.

Exclusion criteria

• Esophagectomy for ischemic or caustic oesophagitis, and patients lost for follow-up.

Trial design

50 participants in 2 patient groups

Control group

Description:

Esophagectomy alone

Treatment:

Other: Collecting data from the medical record

Study Group

Description:

Preoperative ischemic conditioning before esophagectomy

Treatment:

Other: Collecting data from the medical record