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Preoperative Carbohydrate Loading in Patients Undergoing Day-case Cholecystectomy

U

University of Oulu

Status

Completed

Conditions

Preoperative Care

Treatments

Dietary Supplement: carbohydrate rich drink

Study type

Interventional

Funder types

Other

Identifiers

NCT03757208
Uoulu 192/2012

Details and patient eligibility

About

Background: Preoperative carbohydrate loading has been shown to reduce preoperative discomfort and postoperative nausea and vomiting in general surgical patients. Few studies have been focused on patients undergoing day-case surgery.

Objective: The aim of this prospective randomized study was to determine whether preoperative carbohydrate loading enhanced the recovery of patients undergoing day-case cholecystectomy.

Design: A randomised controlled trial. Setting: Secondary care in a district general and a university hospital in Finland between 2013-2016.

Patients: A total of 113 patients ASA physical status I or II (18-70 yr) undergoing day-case cholecystectomy were included in the study. Exclusion criteria were bleeding or coagulation disorders, BMI >40, dementia, insulin-treated diabetes, migraine, Meniere's disease or a history of alcohol or drug abuse.

Intervention: The carbohydrate rich drink (CHD) group received oral carbohydrate (200 ml) 2-3 h before surgery, and the control (Fasting) group fasted from midnight according to standard protocol.

Main outcome measures: Visual analogue scales (VAS) were used to score six discomfort parameters. The needs for analgesia or antiemetics, the time to drinking, eating and first mobilization after surgery, and the time to discharge and hospital readmission were recorded.

Enrollment

113 patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients between 18-70 yr (ASA physical status I-II) eligible for day-case cholecystectomy

Exclusion criteria

  • Patients with bleeding or coagulation disorders, BMI >40, dementia or suffering from insulin-treated diabetes, migraine, Meniere's disease or with history of alcohol or drug abuse

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

113 participants in 2 patient groups

Fasting group
No Intervention group
Carbohydrate rich drink (CHD) group
Active Comparator group
Treatment:
Dietary Supplement: carbohydrate rich drink

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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