Preoperative Cognitive Impairment Predicts Postoperative Delirium

Zhengzhou University

Status: Completed

Conditions: Cognitive Impairment; Delirium in Old Age; Neurocognitive Disorders

Treatments: Behavioral: Neuropsychological tests

Study type: Observational

Funder types: Other

Identifiers

NCT05798767

PCI and POD

Details and patient eligibility

About

Preoperative cognitive impairment (PCI) may increase the incidence of postoperative delirium (POD), yet screening for cognitive impairment is rarely performed. This study hypothesized that Mini-Cog for preoperative cognitive impairment screening predicts postoperative delirium. Elderly patients (65 years or older) attending Henan Provincial People's Hospital during the trial period who required elective thoracic surgery were recruited into the study.

Full description

We collected data points on demographics and hospital episodes through the electronic medical record the day before surgery. Cognitive function screening (Mini-Cog; the Mini-mental State Examination, MMSE), depression screening (Patient Health Questionnaire-9, PHQ-9), sleep quality assessment (Pittsburgh Sleep Quality Index, PSQI), and pain assessment (Numeric Rating Scale, NRS) were performed, and the time spent on Mini-Cog test and MMSE assessment was recorded. The Short Confusion Assessment Method (CAM) was administered once per day on postoperative days 1 to 5 to evaluate delirium.

Enrollment: 150 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. 65 years of age or older,
2. elective thoracic surgery,
3. under general anesthesia.

Exclusion criteria

1. history of psychiatric disorders,
2. use of any antipsychotic drugs,
3. ASA score >3
4. severe visual, hearing, or physical dysfunction unable to complete the scale
5. advanced malignant tumors of the chest with distant metastases to bone, liver, etc.,
6. history of general anesthesia surgery in the last six months.

Trial design

150 participants in 2 patient groups

PCI group

Description:

Patients with a Mini-Cog score of 3 or less were in the PCI group

Treatment:

Behavioral: Neuropsychological tests

Normal group

Description:

Patients with a Mini-Cog score of 3 or 4 were in the normal group

Treatment:

Behavioral: Neuropsychological tests