Preoperative Corneal Thickness and Postoperative Visual Outcomes After Posterior Lamellar Corneal Transplant (TransCor)

Centre Hospitalier Régional Metz-Thionville

Status: Completed

Conditions: Corneal Changes of Membranes

Study type: Observational

Funder types: Other

Identifiers

NCT03355911

2016-07Obs-CHRMT

Details and patient eligibility

About

To evaluate the impact of preoperative corneal thickness on visual outcomes following Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)

Full description

Patients underwent DSAEK or DMEK for endothelial dysfunction, from October 2013 to November 2016. Patients aged > 18 years and with an indication for posterior lamellar graft surgery, such as Fuchs dystrophy, were included. Exclusion criteria included a history of penetrating keratoplasty in the study eye and a need for a penetrating keratoplasty following endothelial graft failure. Visual acuity, central corneal thickness (CCT) and graft thickness were measured preoperatively, and at postoperative day 7 and months 1, 3 and 6.

Enrollment: 113 patients

Sex

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically indicated need for posterior lamellar graft surgery (DSAEK or DMEK) such as:

  • Fuchs dystrophy,
  • pseudophakic bullous decompensation
  • or other endothelial dysfunction corneal

Exclusion criteria

• were a history of penetrating keratoplasty in the indicated eye
• the technical inability of preoperative CCT measurement
• the need for a penetrating keratoplasty following endothelial graft failure
• severe postoperative complications resulting in unquantifiable visual acuity