Preoperative Gabapentine for Carpal Tunnel

Federal University of São Paulo

Status and phase: Completed; Phase 3

Conditions: Carpal Tunnel Syndrome

Treatments: Other: Sugar pill; Drug: Gabapentine

Study type: Interventional

Funder types: Other

Identifiers

NCT01632215

CEP 0223/09

Details and patient eligibility

About

The purpose of this study was to evaluate the postoperative analgesic effect of preoperative gabapentine for carpal tunnel syndrome surgery.

Full description

There was studied 40 patients. Group 1 patients received 600 mg of gabapentin 1 hour before surgery; G2 received placebo 1 hour before surgery.

Anesthesia was regional intravenous block. Postoperative analgesia when needed was with acetaminophen. If needed was administered codeine. The evaluation of neuropathic pain was made by DN4 questionnaire. Pain intensity was assessed by numeric scale at block and after 30min, 1h, 2h, 2wk, 4wk, 6m. It was noted the duration of analgesia, and the amount of acetaminophen and codeine.

The statistical program used for analysis of the results was the Instat Graph

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• carpal tunnel syndrome

Exclusion criteria

• disorientation, psychiatric disease, myocardial ischemia, hypertension, arrhythmia, another pain syndrome, drug user, and pregnant

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 2 patient groups, including a placebo group

preoperative gabapentine,

Experimental group

Description:

Gabapentine

Treatment:

Drug: Gabapentine

sugar pill

Placebo Comparator group

Description:

Placebo group

Treatment:

Other: Sugar pill